Depression, inflammation, and epidermal growth factor receptor (EGFR) status in metastatic non-small cell lung cancer: A pilot study.

Jamie M Jacobs,Lara Traeger,Justin Eusebio,Naomi M Simon,Lecia V Sequist,Joseph A Greer,Jennifer S Temel,William F Pirl

Journal of Psychosomatic Research（2017）

引用 26|浏览8

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摘要

•EGFR mutations in stage IV non-small cell lung cancer (NSCLC) protect against depression.•Patients with EGFR mutations exhibit elevated proinflammatory marker TNF-α.•Genotyping may be used as an indicator for patients with NSCLC at risk for depression.

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关键词

Non-small cell lung cancer,Genotyping,Epidermal growth factor receptor,Depression,Inflammatory cytokines,Oncology

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