Disability in progressive MS is associated with T2 lesion changes.

C Ammitzbøll,T B Dyrby,M Lyksborg,K Schreiber,R Ratzer,J Romme Christensen,P Iversen,M Magyari,E Garde, P S Sørensen,H R Siebner,F Sellebjerg

Multiple Sclerosis and Related Disorders（2018）

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摘要

•MRI and disability in progressive MS, an extensive study.•Disability in progressive MS is associated with increased T2 lesion volume.•EDSS worsening in progressive MS is associated with reduced MTR in T2 lesions.•In progressive MS, MD in T2 lesions correlate with performance in T25FW and PASAT.

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关键词

Magnetic resonance imaging,Multiple sclerosis,Magnetisation transfer ratio,Diffusion tensor imaging,Expanded disability status scale,Multiple sclerosis functional composite

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