Outcome of hematopoietic cell transplantation for DNA double-strand break repair disorders.

Journal of Allergy and Clinical Immunology（2018）

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摘要

RIC HCT resolves DNA repair disorder-associated immunodeficiency. Long-term follow-up is required for secondary malignancy surveillance. Routine HCT for AT is not recommended.

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关键词

Ataxia-telangiectasia,Cernunnos-XLF deficiency,DNA repair disorders,DNA ligase IV deficiency,hematopoietic stem cell transplantation,Nijmegen breakage syndrome

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