VEGF gene therapy cooperatively recruits molecules from the immune system and stimulates cell homing and angiogenesis in refractory angina.

Bruna Eibel,Melissa M Markoski,Clarissa G Rodrigues,Thiago Dipp, Felipe B de Salles,Imarilde I Giusti,Nance B Nardi,Rodrigo D M Plentz,Renato A K Kalil

Cytokine（2017）

引用 3|浏览12

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摘要

•VEGF gene therapy is influenced by chronic inflammatory process.•Immune system cell and angiogenic expression are time-dependent by gene therapy.•VEGF gene therapy is influenced by continuous pharmacological treatment.•Gene therapy provided an angiogenic process at time line.

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关键词

Coronary artery disease,Refractory angina,Vascular endothelial growth factor,Gene therapy,Cell homing,Angiogenesis

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