Immunization with an adenovirus-vectored TB vaccine containing Ag85A-Mtb32 effectively alleviates allergic asthma

    Yiling Zhang
    Yiling Zhang
    Ying Feng
    Ying Feng
    Xianmiao Ye
    Xianmiao Ye
    Qian Wang
    Qian Wang
    Xuehua Zheng
    Xuehua Zheng
    Xiang Gao
    Xiang Gao

    Journal of molecular medicine (Berlin, Germany), 2018.

    Cited by: 3|Bibtex|Views36|Links
    WOS
    Keywords:
    Adenoviral vectorAllergic asthmaCytokinesImmunizationMycobacterial antigens

    Abstract:

    •Ad5-gsgAM elicits Th1 responses and suppresses Th2-mediated allergic asthma in mice. •Ad5-gsgAM inhibits IL-33/ST2 axis by reducing IL-33 secretion but not ILC2 recruiting. •Treg is essential for modulating Th2 responses and IL-33/ST2 axis by Ad5-gsgAM.

    Code:

    Data:

    Your rating :
    0

     

    Tags
    Comments