Evaluation bias in objective response rate and disease control rate between blinded independent central review and local assessment: a study-level pooled analysis of phase III randomized control trials in the past seven years

    Jianrong Zhang
    Jianrong Zhang
    Yiyin Zhang
    Yiyin Zhang
    Shiyan Tang
    Shiyan Tang
    Hengrui Liang
    Hengrui Liang
    Difei Chen
    Difei Chen
    Qihua He
    Qihua He
    Yu Huang
    Yu Huang
    Xinyu Wang
    Xinyu Wang
    Kexin Deng
    Kexin Deng
    Shuhan Jiang
    Shuhan Jiang
    Jiaqing Zhou
    Jiaqing Zhou

    Annals of translational medicine, Volume 5, Issue 24, 2017, Pages 481

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    Keywords:
    Blind independent central reviewrandomized control trials (RCTs)tumor assessment

    Abstract:

    Blind independent central review remained irreplaceable to monitor local assessment, but its complete-case implementation may be unnecessary.

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