A divergent and metal free synthesis of sulfoximine tethered imidazoles, imidazopyridines, imidazothiazoles, imidazobenzothiazines, thiazoles and selenazoles

S R K Battula,V P Rama Kishore Putta, G V Subbareddy, I E Chakravarthy,V Saravanan

Organic & Biomolecular Chemistry（2017）

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摘要

A divergent and metal free approach has been successfully developed for the synthesis of sulfoximine tethered heterocycles. A key a-bromoalkanone intermediate 3b has been reported for the first time. Various sulfoximine tethered imidazoles, imidazopyridines, thiozoloimidazoles, imidazobenzothiazines, thiazoles and selenazoles are made from this common sulfoximine building block.

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