Hollow hyaluronic acid particles by competition between adhesive and cohesive properties of catechol for anticancer drug carrier.

Jeongwook Lee,Ki Chun Yoo,Jaehyoung Ko,Bowon Yoo,Joohuei Shin,Su-Jae Lee,Daewon Sohn

Carbohydrate Polymers（2017）

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摘要

•Catechol modified hyaluronic acid (HA-CA) shell was fabricated for drug carrier.•Redox transition of catechol with pH is a key to modulate behavior of HA-CA shell.•DOX loaded HA-CA particles show pH-triggered release behavior and cytotoxic effect.

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关键词

Hyaluronic acid,Catechol,Redox transition,Adhesive,pH triggered release

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