Potential hepatic toxicity of buprofezin at sublethal concentrations: ROS-mediated conversion of energy metabolism.

Xiaotong Ji,Tingting Ku,Na Zhu,Xia Ning,Wei Wei,Guangke Li,Nan Sang

Journal of Hazardous Materials（2016）

引用 33|浏览0

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摘要

•Liver was one of the major organs for buprofezin accumulation and toxicity.•Buprofezin promoted the shunting of energy metabolism.•ROS participated in buprofezin-mediated cytochrome c oxidase inhibition.

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关键词

TCA cycle,ROS,mtDNA,SCO1,COX17,CS,OGDH,IDH2,FH,PFKFB3,LDHB,MMP,MRC

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