Compartmentalized dynamics of cytomegalovirus replication in treated congenital infection.

•Virus was detectable in the blood at baseline in only 15/17 neonates.•The median half-life (T1/2) of virus decline in blood in neonates was 2.4 days.•T1/2 is similar to adults so prolonged viraemia in infants is not explained by this.•Virus dynamics differ between blood and urine which may inform future studies.