CD4 and CD4/CD8 ratio progression in HIV-HCV infected patients after achievement of SVR.

Journal of Clinical Virology(2016)

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摘要
•To evaluate long-term effects of HCV eradication in HIV-HCV co-infected patients.•SVR (sustained virological response) and non-SVR groups compared.•Decreasing FIB-4 and APRI trends observed after SVR (median 8 year-follow-up).•No difference in absolute or percentage CD4 slope and CD4/CD8 ratio trend over time.•Higher mortality in non-SVR group, with no difference in AIDS and non-AIDS events.
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关键词
CD4,CD4/CD8 ratio,SVR,HIV-HCV co-infection,FIB-4,APRI,Liver fibrosis
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