Both ketamine and NBQX attenuate alcohol drinking in male Wistar rats.
Neuroscience Letters(2018)
摘要
•Acute low dose ketamine reduced alcohol intake but not alcohol-related behavioural effects.•Acute low dose NBQX reduced alcohol intake but not alcohol-related behavioural effects.•NMDA or AMPA/kainate receptor antagonists may have treatment potential in alcohol use disorder.
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关键词
Alcoholism,Alcohol use disorder,Glutamatergic receptors,NMDA receptor,AMPA receptor,Kainate receptor
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