Membrane protein crystallization in micelles conjugated by nucleoside base-pairing: A different concept.

Basavaprabhu Hosamani,Raju R Kale,Hemlata Sharma,Ellen Wachtel,Ellina Kesselman,Dganit Danino,Noga Friedman,Mordechai Sheves,Irishi N N Namboothiri,Guy Patchornik

Journal of Structural Biology（2016）

引用 6|浏览8

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摘要

Spontaneous partitioning of hydrophobic G and C nucleoside derivatives into nonionic micelles induces extensive conjugation via base-pairing at the micellar interface. This creates an environment which promotes crystallization of the membrane protein, bacteriorhodopsin (bR).

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关键词

Membrane Proteins,Membrane Curvature

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