Development and clinical validation of a circulating tumor DNA test for the identification of clinically actionable mutations in non-small cell lung cancer

    Liping Liu
    Liping Liu
    Han Liu
    Han Liu
    Zu Liu
    Zu Liu
    Jingjing Wang
    Jingjing Wang
    Qiuhua Deng
    Qiuhua Deng
    Meihua Tan
    Meihua Tan

    Genes, chromosomes & cancer, 2017.

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    Keywords:
    Actionable mutationNGSNSCLCctDNA

    Abstract:

    Molecular analysis of potentially actionable mutations has become routine practice in oncological pathology. However, testing a wide range of oncogenes and mutations can be technically challenging because of limitations associated with tumor biopsy. Circulating tumor DNA (ctDNA) is a potential tool for the noninvasive profiling of tumors....More

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