Comparing evolutionary distances via adaptive distance functions.

Journal of Theoretical Biology(2018)

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摘要
•Analysis of the basic problem of comparing the lengths of two K2P paths.•A method for comparing two paths based on “adaptive distance”, which is nearly as accurate as maximum-likelihood, but much more efficient.•Extension of distance comparison methods to quartet inference.•Characterization of topological bias and possible causes.
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关键词
Distance-based phylogenetic reconstruction,DNA substitution models,Adaptive distance estimation,Distance comparison,Fisher’s linear discriminant
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