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Structure Based Design of Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors from a Phenotypic Screen

Daniel S. Palacios,Erik Meredith,Toshio Kawanami,Christopher Adams,Xin Chen,Veronique Darsigny, Erin Geno,Mark Palermo,Daniel Baird,Geoffrey Boynton,Scott A. Busby,Elizabeth L. George,Chantale Guy,Jeffrey Hewett,Laryssa Tierney,Sachin Thigale,Wilhelm Weihofen,Louis Wang,Nicole White, Ming Yin,Upendra A. Argikar

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS（2018）

Cited 15|Views48

Key words

NAMPT,In silico screen,Structure based drug design,Cyclopropane,Nicotinamide phosphoribosyltransferase

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