Cervicovaginal Inflammation Facilitates Acquisition of Less Infectious HIV Variants

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Volume 64, Issue 1, 2017, Pages 79-82.

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    Keywords:
    HIV acquisitioncytokinefemale genital tractinflammationviral infectivity

    Abstract:

    We evaluated whether genital inflammation affects the selection of the transmitted virus. Among South African women, we found that preinfection genital inflammation facilitates transmission of less infectious human immunodeficiency virus, but highly infectious viruses are able to establish infection regardless of inflammation status. This...More

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