Orally-dissolving film for sublingual and buccal delivery of ropinirole.

•Crystalline orally-dissolving films of ropinirole were prepared.•The oral films exhibit fast disintegration, dissolution; and are physical stable.•The oral films are non-cytotoxic and metabolically stable in oral mucosal tissues.•The oral films exhibit fast drug absorption.•The bioavailability of ropinirole was significantly improved by the oral films.