Maternal Type 1 diabetes activates stress response in early placenta

Placenta(2017)

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摘要
•Maternal T1DM upregulates stress responsive proteins in early placenta.•We conclude that maternal T1DM increases cellular stress in early placenta.•Cellular stress may contribute to the risk for pregnancy pathologies associated with T1DM.
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关键词
Type 1 diabetes,Stress response,Oxidative stress,First trimester placenta,Trophoblast
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