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Discovery and Optimization of Selective FGFR4 Inhibitors Via Scaffold Hopping

Yikai Wang,Zhengxia Chen,Meibi Dai, Peipei Sun, Chunqiu Wang, Yang Gao, Haixia Zhao, Wenqin Zeng,Liang Shen,Weifeng Mao, Tian Wang,Guoping Hu,Jian Li,Shuhui Chen,Chaofeng Long,Xiaoxin Chen,Junhua Liu,Yang Zhang

Bioorganic & Medicinal Chemistry Letters(2017)

Cited 21|Views2
Key words
Hepatocellular carcinoma,Fibroblast growth factor 19,Fibroblast growth factor receptor 4,Covalent inhibitor,Isoform selective
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