Genetics of Bi-component leukocidin and drug resistance in nasal and clinical Staphylococcus aureus in Lagos, Nigeria.

•Twelve (12) MRSA carrying staphylococcal cassette chromosome mecA type I, III, and IV elements were identified and type I dominated.•High rates (lukE/D and lukPV) were recorded, the occurrence of lukE/D was 100% (MRSA), lukPV (MSSA) dominated.•High rate of lukE/D and lukPV were recorded, however, the occurrence of lukE/D was 100% among MRSA, while lukPV dominated MSSA strains.•Staphylococcus aureus with onlyl (luk-PV), (lukE/D) and combined (lukE/D and lukPV) toxins were found.•Hemolysin (hlgA/B) genes were not detected in all the 92 S. aureus.