Non-alcoholic fatty liver disease impairs expression of the type II inositol 1,4,5-trisphosphate receptor.

Tanaporn Khamphaya,Natsasi Chukijrungroat,Vitoon Saengsirisuwan,Kisha A Mitchell-Richards,Marie E Robert,Albert Mennone,Meenakshisundaram Ananthanarayanan,Michael H Nathanson,Jittima Weerachayaphorn

HEPATOLOGY（2018）

引用 40|浏览27

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摘要

These findings suggest that fatty liver induces a c-Jun-mediated decrease in ITPR2 in hepatocytes. This may account for the impaired liver regeneration that occurs in NAFLD. This article is protected by copyright. All rights reserved.

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关键词

Calcium release channel,Hepatic steatosis,Liver regeneration,Steatohepatitis,c-Jun

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