Passive immunotherapy for Middle East Respiratory Syndrome coronavirus infection with equine immunoglobulin or immunoglobulin fragments in a mouse modelWOS

    Yongkun Zhao
    Yongkun Zhao
    Chong Wang
    Chong Wang
    Boning Qiu
    Boning Qiu
    Hongli Jin
    Hongli Jin
    Weiwei Gai
    Weiwei Gai
    Xuexing Zheng
    Xuexing Zheng
    Feihu Yan
    Feihu Yan
    Cited by: 5|Bibtex|14|

    Antiviral research, Volume 1372017, Pages 125-130.

    Keywords:
    Animal modelEquine immune serumF(ab’)(2) fragmentImmunoglobulinMiddle East Respiratory Syndrome coronavirus

    Abstract:

    Middle East Respiratory Syndrome (MERS) is a highly lethal pulmonary infection caused by a coronavirus (CoV), MERS-CoV. With the continuing spread of MERS-CoV, prophylactic and therapeutic treatments are urgently needed. In this study, we prepared purified equine F(ab') from horses immunized with MERS-CoV virus-like particles (VLPs) expre...More
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