Passive immunotherapy for Middle East Respiratory Syndrome coronavirus infection with equine immunoglobulin or immunoglobulin fragments in a mouse modelWOS
Antiviral research, Volume 1372017, Pages 125-130.
Keywords:Animal modelEquine immune serumF(ab’)(2) fragmentImmunoglobulinMiddle East Respiratory Syndrome coronavirus
Middle East Respiratory Syndrome (MERS) is a highly lethal pulmonary infection caused by a coronavirus (CoV), MERS-CoV. With the continuing spread of MERS-CoV, prophylactic and therapeutic treatments are urgently needed. In this study, we prepared purified equine F(ab') from horses immunized with MERS-CoV virus-like particles (VLPs) expre...More