Characterization of APOE and TOMM40 allele frequencies in the Japanese population.
Alzheimer's & Dementia: Translational Research & Clinical Interventions(2017)
摘要
•Linkage between the translocase of outer mitochondrial membrane 40 (TOMM40′523) and apolipoprotein E (APOE) allele differs depending on the population.•The APOE ε3–TOMM40′523 short haplotype is less frequent in the Japanese population than in Caucasian ones.•The APOE ε3–TOMM40′523 long and very long haplotypes are more frequent in the Japanese population than in Caucasian ones.
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关键词
Allele frequency,Alzheimer's disease,Apolipoprotein E (APOE),Japanese,Poly-thymine (poly-T) variants,Translocase of outer mitochondrial membrane 40 (TOMM40)
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