Adjuvant-active aqueous extracts from Artemisia rupestris L. improve immune responses through TLR4 signaling pathway.

Ailian Zhang,Yu Yang,Yan Wang,Gan Zhao,Xiumei Yang,Danyang Wang,Bin Wang

Vaccine（2017）

引用 18|浏览4

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摘要

•AEAR as a novel adjuvant can enhance antigen specific immune response without obvious side effect.•AEAR can be used for human and animal vaccines with a minimum of undesirable adverse effect.•The enhanced adjuvant effect is mediated by promoting DC maturation via TLR4 signaling pathway.

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关键词

Aqueous extract,Artemisia rupestris L.,Adjuvant effect,Dendritic cells,TLR4

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