Associations between NOD2, IRGM and ORMDL3 polymorphisms and pediatric-onset inflammatory bowel disease in the Lithuanian population.

Medicina(2016)

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摘要
The results confirmed that polymorphisms in NOD2 (Leu1007insC) and IRGM genes are associated with increased risk of CD; whereas the ORMDL3 variant is associated with susceptibility to UC in the Lithuanian early-onset IBD population.
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关键词
Inflammatory bowel diseases,Crohn's disease,Ulcerative colitis,Early onset,Single nucleotide polymorphism
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