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Bioactivation of Cyclopropyl Rings by P450: an Observation Encountered During the Optimisation of a Series of Hepatitis C Virus NS5B Inhibitors

Xenobiotica(2017)

Cited 10|Views47
Key words
Bioactivation,cyclopropyl,glutathione conjugates,hepatitis C virus inhibitor,LC/MS,medicinal chemistry,metabolism,NMR,P450
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