Hypoxia-preconditioned mesenchymal stem cells ameliorate ischemia/reperfusion-induced lung injury

    Yung-Yang Liu
    Yung-Yang Liu
    Chi-Huei Chiang
    Chi-Huei Chiang
    Chih-Feng Chian
    Chih-Feng Chian
    Chen-Liang Tsai
    Chen-Liang Tsai
    Wei-Chih Chen
    Wei-Chih Chen

    PloS one, Volume 12, Issue 11, 2017.

    Cited by: 12|Bibtex|Views0|Links
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    Abstract:

    Hypoxic MSCs can quickly migrate into extravascular lung tissue and adhere to other inflammatory or structure cells and attenuate I/R lung injury through anti-oxidant, anti-inflammatory and anti-apoptotic mechanisms. However, the dose of MSCs needs to be optimized to prevent pulmonary embolism and thrombosis.

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