Electroconvulsive stimulation transiently enhances the permeability of the rat blood-brain barrier and induces astrocytic changes.

Masanobu Ito,Kuerban Bolati, Tomoya Kinjo,Koichiro Ichimura,Akiko Furuta,Declan M McLoughlin,Toshihito Suzuki,Heii Arai

Brain Research Bulletin（2017）

引用 7|浏览15

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摘要

•ECS enhance permeability of BBB with astrocytic changes.•Enhancement of permeability of BBB with ECS is reversible.•Harmful phenomena were not found after ECS.•Enhancing the permeability may allow the access of medications to the brain.

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关键词

Depression,ECT,BBB,Astrocyte,Tight junction,Neurovascular unit

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