A Gene Family-led Meta-Analysis of Drug-Target Interactions

Qiong Cheng,Saurabh Mehta,Tudor Oprea,Stephan Schurer

PROCEEDINGS 2018 IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICINE (BIBM)（2018）

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摘要

The shift from "magic bullets" to "magic shotguns" has prospered the pharmaceutical industry, wh belief is that a drug that "hits" multiple sensitive nodes belonging target interactions, profiled by the "magic shotguns" design paradigm, have emerged from diverse labs. properties that drug set a stage for the analysis of the mechanism of action of

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关键词

polypharmocology;ontology;drug-target interactions;information content;meta-analysis

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