Fair Deep Learning Prediction for Healthcare Applications with Confounder Filtering.

The rapid development of deep learning methods has permitted the fast and accurate medical decision making from complex structured data, like CT images or MRI. However, some problems still exist in such applications that may lead to imperfect predictions. Previous observations have shown that, confounding factors, if handled inappropriately, will lead to biased prediction results towards some major properties of the data distribution. In other words, naively applying deep learning methods in these applications will lead to unfair prediction results for the minority group defined by the characteristics including age, gender, or even the hospital that collects the data, etc. In this paper, extending previous successes in correcting confounders, we propose a more stable method, namely Confounder Filtering, that can effectively reduce the influence of confounding factors, leading to better generalizability of trained discriminative deep neural networks, therefore, fairer prediction results. Our experimental results indicate that the Confounder Filtering method is able to improve the performance for different neural networks including CNN, LSTM, and other arbitrary architecture, different data types including CT-scan, MRI, and EEG brain wave data, as well as different confounding factors including age, gender, and physical factors of medical devices etc