Fuzzy-Rough Entropy Measure and Histogram Based Patient Selection for miRNA Ranking in Cancer.

IEEE/ACM Transactions on Computational Biology and Bioinformatics(2018)

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摘要
MicroRNAs (miRNAs) are known as an important indicator of cancers. The presence of cancer can be detected by identifying the responsible miRNAs. A fuzzy-rough entropy measure (FREM) is developed which can rank the miRNAs and thereby identify the relevant ones. FREM is used to determine the relevance of a miRNA in terms of separability between normal and cancer classes. While computing the FREM for...
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关键词
Cancer,Entropy,Histograms,Mutual information,Redundancy,Proteins,Support vector machines
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