Antidepressant effects of focused ultrasound induced blood-brain-barrier opening

Skyler J. Mooney,José N. Nobrega,Anthony J. Levitt,Kullervo Hynynen

Behavioural Brain Research（2018）

引用 17|浏览25

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摘要

•The blood-brain-barrier of rats is transiently opened with focused ultrasound.•2 weekly treatments results in short-term antidepressant effects.•Longer-term effects are absent at 5 weeks post-treatment.

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关键词

Focused ultrasound,Forced swim test,Blood-brain barrier,Antidepressants,Neurogenesis

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