Lithium and memantine improve spatial memory impairment and neuroinflammation induced by β-amyloid 1-42 oligomers in rats

J. Budni, D.P. Feijó,H. Batista-Silva,M.L. Garcez,F. Mina, T. Belletini-Santos, L.R. Krasilchik, A.P. Luz,G.L. Schiavo,J. Quevedo

Neurobiology of Learning and Memory（2017）

引用 34|浏览6

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摘要

•Association of lithium and memantine treatment improved spatial memory.•Lithium and memantine treatment increased IL-4 levels.•Lithium and memantine treatment decreased IL-1β levels.•Lithium and memantine treatment decreased TNF-α levels.

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关键词

Alzheimer’s disease,Dementia,β-Amyloid 1-42,Lithium,Memantine,Spatial memory,Cytokines

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