Combinatorics of Tandem Duplication Random Loss Mutations on Circular Genomes.

Tom Hartmann,An-Chiang Chu,Martin Middendorf,Matthias Bernt

IEEE/ACM Transactions on Computational Biology and Bioinformatics（2018）

引用 15|浏览46

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摘要

The tandem duplication random loss operation (TDRL) is an important genome rearrangement operation in metazoan mitochondrial genomes. A TDRL consists of a duplication of a contiguous set of genes in tandem followed by a random loss of one copy of each duplicated gene. This paper presents an analysis of the combinatorics of TDRLs on circular genomes, e.g., the mitochondrial genome. In particular, r...

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Genomics,Sorting,Transforms,Animals,Biological cells,Computer science,Electronic mail

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