Continuous Assessment of Levodopa Response in Parkinson's Disease Using Wearable Motion Sensors.

Objective: Fluctuations in response to levodopa in Parkinson's disease (PD) are difficult to treat as tools to monitor temporal patterns of symptoms are hampered by several challenges. The objective was to use wearable sensors to quantify the dose response of tremor, bradykinesia, and dyskinesia in individuals with PD. Methods: Thirteen individuals with PD and fluctuating motor benefit were instru...