Olanzapine-Based Triple Regimens Versus Neurokinin-1 Receptor Antagonist-Based Triple Regimens in Preventing Chemotherapy-Induced Nausea and Vomiting Associated with Highly Emetogenic Chemotherapy: A Network Meta-Analysis

    The oncologist, 2018.

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    Keywords:
    Chemotherapy‐induced nausea and vomitingHighly emetogenic chemotherapyNauseaNetwork meta‐analysisNeurokinin‐1 receptor antagonistsMore(1+)

    Abstract:

    The current antiemetic prophylaxis for patients treated with highly emetogenic chemotherapy (HEC) included the olanzapine-based triplet and neurokinin-1 receptor antagonists (NK-1RAs)-based triplet. However, which one shows better antiemetic effect remained unclear.We systematically reviewed 43 trials, involving 16,609 patients with HEC, ...More

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