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A Dipolar Cycloaddition Reaction to Access 6-Methyl-4,5,6,7-tetrahydro-1h-[1,2,3]triazolo[4,5-c]pyridines Enables the Discovery Synthesis and Preclinical Profiling of a P2X7 Antagonist Clinical Candidate.

Journal of Medicinal Chemistry(2017)

Cited 60|Views51
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