Efficacy and safety of bivalirudin in coronary artery disease patients with mild to moderate chronic kidney disease: Meta-analysis.

Xiaofang Zeng,A Michael Lincoff,Stefanie Schulz-Schüpke,Philippe Gabriel Steg,Yedid Elbez,Roxana Mehran,Gregg W Stone,Thomas McAndrew,Jianhui Lin, Xindan Zhang,Wenhai Shi,Han Lei,Zhicheng Jing,Wei Huang

Journal of Cardiology（2018）

引用 5|浏览21

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摘要

•Impaired renal function does not influence the safety profile of bivalirudin.•Bivalirudin is suitable for cardiovascular disease patients with renal insufficiency.•The use of bivalirudin decreases bleeding events more than heparin plus glycoprotein IIb/IIIa inhibitors (GPIs).•Similar ischemic events were observed between bivalirudin and heparin plus GPIs.

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关键词

Bivalirudin,Chronic kidney disease,Coronary artery disease,Efficacy,Safety

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