Bariatric surgery versus conservative management for morbidly obese patients in Spain: a cost-effectiveness analysis.

EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH(2018)

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摘要
Background: We assessed the cost-effectiveness of bariatric surgery (BS) versus conservative management (CM) for treating morbid obesity in Spain.Methods: We developed a probabilistic Markov model to estimate health outcomes, quality-adjusted life years (QALY), life years gained (LYG), and costs over lifetime and 10-year horizons. Combined common BS procedures were compared with CM. Clinical and utility inputs were obtained from the literature and resource use and costs from local sources (Euro2017).Results: Over the 10-year horizon, BS led to a cost increment of Euro9,386 and 1.6 additional QALY (Euro5,966/QALY). Leading to 0.6 LYG and 4.4 QALY gains and Euro300/patient average cost savings over lifetime, BS could potentially significantly reduce diabetes and cardiovascular disease risk over the considered horizons. Despite short-term cost reductions, surgery delay may lead to significant clinical benefits loss.Conclusions: Compared to CM, BS is a more effective and less costly alternative for treating morbid obesity in Spain.
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关键词
Bariatric surgery,obesity,cost-effectiveness,economic evaluation,Markov,Spain
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