A comprehensive review of uncommon EGFR mutations in patients with non-small cell lung cancer.

Lung Cancer（2017）

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摘要

•Uncommon EGFR mutations are more prevalent in males and smokers.•The most prevalent uncommon mutation is 20INS (31%) followed by G791X (21%).•Chemotherapy might be better than TKIs for 20INS, T790M and worse for other mutations.

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关键词

Uncommon EGFR mutation,Epidemiology,Erlotinib,Exon 20 insertion,Gefitinib,T790M mutation

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