Forensic evaluation of STR typing reliability in lung cancer

•75 lung cancer tissue samples were performed to evaluate the reliability of STR markers in malignant tissue as a source for forensic analysis.•Our study suggested that older patients with advanced stage of progression exhibited a higher frequency of STR variation.•Two STR loci, D2S441 and Penta E may select as potential stable STR loci used in lung cancer tissues for forensic analysis.