Disease trends over time and CD4 + CCR5 + T-cells expansion predict carotid atherosclerosis development in patients with systemic lupus erythematosus.

A Baragetti,G A Ramirez,M Magnoni,K Garlaschelli,L Grigore,M Berteotti,I Scotti,E Bozzolo,A Berti,P G Camici,A L Catapano,A A Manfredi,E Ammirati,G D Norata

Nutrition, Metabolism and Cardiovascular Diseases（2018）

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摘要

•SLE patients show increased 5-years carotid atherosclerosis development compared to general population.•SLE activity and its trends over time are associated and predict carotid atherosclerosis developments.•High percentages of circulating CD4+CCR5+ T cell subsets predict increased carotid atherosclerosis development over follow-up.

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关键词

Systemic lupus erythematosus,Carotid atherosclerosis,Adaptive immunity

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