In vitro and in vivo evaluation of 10-hydroxycamptothecin-loaded poly (n-butyl cyanoacrylate) nanoparticles prepared by miniemulsion polymerization.

Xin Jin,Sajid Asghar,Xieting Zhu,Zhipeng Chen,Cihui Tian,Lining Yin,Qineng Ping,Yanyu Xiao

Colloids and Surfaces B: Biointerfaces（2018）

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摘要

Scheme for constructing a 10-hydroxycamptothecin-loaded poly (n-butyl cyanoacrylate) nanoparticles (HCPT-PBCA-NPs) as a carrier for oral administration.

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关键词

10-Hydroxycamptothecin,n-Butyl cyanoacrylate,Miniemulsion polymerisation,Oral bioavailability,Pharmacokinetics

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