Cytokinesis requires localized β-actin filament production by an actin isoform specific nucleator

Nature communications, Volume 8, Issue 1, 2017, Pages 1530-1530.

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Abstract:

Cytokinesis is initiated by the localized assembly of the contractile ring, a dynamic actomyosin structure that generates a membrane furrow between the segregating chromosomal masses to divide a cell into two. Here we show that the stabilization and organization of the cytokinetic furrow is specifically dependent on localized β-actin fila...More

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