Exploring the impact of route of administration on medication acceptance in hospitalized patients: Implications for venous thromboembolism prevention.

•Missed doses of VTE prophylaxis are a common and clinically significant patient care defect.•Subcutaneous VTE prophylaxis doses are missed 4-fold more often than oral infectious disease and cardiac prophylaxis.•Ninety percent of non-administered doses of VTE prophylaxis are refused by patients or family members.•Availability of an oral medication for VTE prophylaxis could significantly reduce non-administration and preventable VTE.