BDNF gene and obsessive compulsive disorder risk, symptom dimensions and treatment response.

Reshma Jabeen Taj M J,Suhas Ganesh,Tulika Shukla,Sayali Deolankar,Ravi K Nadella,Somdatta Sen,Meera Purushottam,Y C Janardhan Reddy,Sanjeev Jain,Biju Viswanath

Asian Journal of Psychiatry（2018）

引用 28|浏览5

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摘要

•A functional single nucleotide polymorphism in BDNF gene rs6265 seems to confer protective effect on obsessive compulsive disorder.•rs6265 (196G/A) is responsible for substitution of valine by methionine on 66th amino acid position.•The protective effect seems to be pronounced in persons with a specific symptom dimension of contamination-washing

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关键词

BDNF,OCD,Response,Symptom dimension,Val66Met

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