Investigating the efficacy of a combination Aβ-targeted treatment in a mouse model of Alzheimer's disease.

Mingzhe Liu,Stefan Jevtic,Kelly Markham-Coultes,Nicholas P K Ellens,Meaghan A O'Reilly,Kullervo Hynynen,Isabelle Aubert,JoAnne McLaurin

Brain Research（2018）

引用 29|浏览18

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摘要

•Treatments reduced amyloid load and astrocyte activation.•Microglial phagocytosis and activation were increased by treatments.•MRIgFUS/BAM10/scyllo-inositol treatment was not statistically different from scyllo-inositol treatment alone.

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关键词

Aβ,AD,BBB,CNS,GFAP,MRI,MRIgFUS,SI,SMIT1,SMIT2

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