Astrocytic glutamatergic transporters are involved in Aβ-induced synaptic dysfunction.

Brain Research（2018）

引用 39|浏览21

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摘要

•First time tested TFB-TBOA effect on the hippocampal LTP.•Systemic compare the several glutamate transporters inhibitors effect on the LTP and LTD, and a LTP/LTD curve.•Both Aβ oligomers and glutamate transporter inhibitors share similar mechanisms on the synaptic dysfunction.

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关键词

Glutamate transporters,Synaptic plasticity,Long-term potentiation,TBOA,Astrocytes,Alzheimer’s disease

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