IgG glycosylation and DNA methylation are interconnected with smoking.
Biochimica et Biophysica Acta (BBA) - General Subjects(2018)
摘要
•An epigenome-wide association study including 3000 individuals from four cohorts was performed.•DNA methylation within 5 genomic locations is associated with IgG glycosylation.•DNA methylation mediated the effects of smoking on IgG glycosylation.
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关键词
DNA methylation,IgG glycosylation,Smoking,EWAS,Mediation
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